Preheat Oven: Preheat your oven to 375°F (190°C) and lightly grease a standard 9x5-inch loaf pan with non-stick spray.
Mix Gently: In a large bowl, combine ground beef, crumbled bacon, cheddar cheese, breadcrumbs, mustard, ketchup, Worcestershire sauce, diced onion, minced garlic, and beaten eggs. Season with salt and pepper.
Do Not Overmix: Gently mix with your hands just until combined. Stop mixing as soon as ingredients are incorporated to keep the meatloaf tender and prevent it from becoming tough.
Shape & Glaze: Transfer the mixture into the loaf pan, pressing gently into an even shape. In a small bowl, whisk the glaze ingredients (ketchup, mustard, brown sugar) and spread generously over the top.
Bake: Bake for 60 to 75 minutes, or until the top glaze is beautifully caramelized and a meat thermometer inserted in the center reads 160°F.
The Secret Rest: Remove from the oven and let it rest in the pan for 10 minutes before slicing. This traps the melted cheese and juices inside so it doesn't crumble!